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Vitamin
B12 research takes 20 years, yields gene
MONTREAL
MUHC and McGill scientists have announced the discovery
of a gene that causes a serious disease and makes it
difficult for the body to deal with vitamin B12. The
research, published in December's Nature Genetics,
identified the gene responsible for combined methylmalonic
aciduria (MMA) and homocystinuria , a crippling illness
which contributes to dementia, heart disease and stroke.
The breakthrough, which took more than 20 years of research,
will make it possible for doctors to diagnose the condition
earlier, assess possible carriers and will lead to new
treatments for the disease.
Your
mother was right: milk's good for you after all
CAMBRIDGE, MA
Despite there being no apparent link between
hypertension and whole milk consumption, people who
drink a great deal of skimmed milk may reduce their
chances of developing the disease by a whopping 50%.
A study published in the November edition of the American
Journal of Clinical Nutrition looked at 6,000 subjects
over two years and compared heavy milk drinkers to those
with low or no consumption of skimmed milk products.
Earlier studies had shown a possible role of lactose
products in staving off hypertension, but this is the
first study to demonstrate the connection in adults.
Prodigious
posteriors render jabs ineffective
CHICAGO
Bigger backsides particularly in women
are becoming a veritable barrier to inoculation say
Irish-based researchers. Dr Victoria Chan and her team
looked at 50 patients in a Dublin hospital. They found
that in jabs to the buttock only 56% of men and 8% of
women properly absorbed the antibody. The solution
and this is going to hurt your patients more than it's
going to hurt you says Dr Chan is longer needles.
The standard needle length of 16mm should be upped to
25mm for average-sized women and all men, and larger
ladies will require a 38mm needle. The findings were
presented on November 28 at the annual meeting of the
Radiological Society of America.
Brits
charge doctor with shielding grossly incompetent colleague
LONDON
One of Britain's top obstetricians, Dr James Owen Drife,
has been called before the General Medical Council (GMC)
to defend his seemingly indefensible decision to vouch
for now-disgraced gynecologist Dr Richard Neale. Dr
Drife is accused of providing unduly rosy references
for Dr Neale despite the fact he was well aware of the
gynecologist's incompetence. If found guilty, Dr Drife
could be removed from the medical register. The GMC
itself is under fire for failing to notice that Dr Neale
was barred from practising medicine in Canada way back
in 1984.
Study
suggests link between creativity and promiscuity
NEWCASTLE UPON
TYNE What do Pablo Picasso and Henry Miller
have in common? They made their living in creative fields
and were legendarily licentious. Now British researchers
have found that creative sorts tend to have a greater
number of sexual partners than the general population.
What's more, researchers found these creative types
are more likely to display "schizotypal" traits than
the population at large. Meanwhile, full-blown schizophrenic
patients had fewer-than-average sexual partners. Investigators
feel the randy artists might help explain how schizophrenic
characteristics remain in the gene pool. The study was
published November 29 in the Proceedings of the Royal
Society B.
How
the body rebels against dieting
NEW YORK
Science now has a good explanation as to why, after
successfully losing weight, dieters so often pile the
avoirdupois back on like it's nobody's business. New
research out of Columbia University suggests the hormone
leptin plays a starring role in fat's unwelcome comeback.
It seems dieting leaves the body in a leptin-starved
state. Investigators looked at 10 subjects on strictly
controlled liquid diets. One group was fed enough to
maintain normal weight, another fed to maintain a 10%
weight loss and the final group was also fed enough
to maintain 10% weight-loss but also given low doses
of leptin. The leptin group didn't display the metabolic,
neuroendocrine and autonomic changes that set the stage
for weight regain. The study appears in the December
1 issue of the Journal of Clinical Investigation.
Caffeine
sets short term memory banks alight
CHICAGO
The world's favourite stimulant, caffeine, can influence
short term memory say Austrian researchers. Dr Florian
Koppelstètter and his team at the Medical University
Innsbruck used functional magnetic resonance imaging
(fMRI) on 15 subjects in order to measure the influence
of caffeine on short term memory tests. Each subject
was scanned once while on 100mg of caffeine and another
time with a placebo. Among the experimental group, the
investigators saw increased activity of both the memory-regulating
frontal lobe, and the attention-grabbing anterior cingulum.
"We were able to show that caffeine modulates a higher
brain function through its effects on distinct areas
of the brain," said Dr Koppelstätter to the press.
He also cautioned that we "still need to learn more
about caffeine's effect on mental resources."
UK
bawdy houses surge in popularity, prompting health concerns
LONDON
In a span of only 10 years the number of British men
courting prostitutes has doubled say researchers in
the November edition of Sexually Transmitted Infections.
In 1990 a survey found 5.6% of men had paid for sex
at one time in their lives, and 2% said it had been
within the past five years. In 2000, these numbers shot
up to 9% of men having paid for sex at least once of
whom 4.2% had done so within the past five years. The
men who paid for sex were a risk-taking lot a
third of them had 10 or more sexual partners in the
past decade and over half had had sex abroad. Chillingly,
only one out of seven British Johns bothered to get
tested for HIV.
Doctor
testimony clears sexsomniac in sexual assault rap
SCARBOROUGH
In a decision that has women's groups across the nation
in an uproar, Jan Luedecke was cleared of sexual assault
charges this week in an Ontario court after testimony
from sleep experts and psychiatrists confirmed the man
suffered from sexsomnia. The disorder, which is relatively
new, is a type of parasomnia in which sufferers engage
in involuntary sexual behaviour during sleep. Sexsomnia
is real, Dr Harvey Moldfosky, director of the University
of Toronto's Centre for Sleep and Chronobiology, told
the Toronto Sun.
New
procedure shakes off persistently clammy hands
CHICAGO
A new, minimally invasive procedure can permanently
cure patients of the awkward and embarrassing symptoms
of palmar hyperhydrosis. No longer will they have to
avoid handshakes and other forms of basic human contact:
CT-guided percutaneous thoracic sympathectomy will dry
up those sweaty hands in a snap. The treatment is a
20-minute procedure that requires no anesthesia and
carries no risk of the nerve damage, bleeding or paralysis
that plagued older therapies. An astonishing 94% of
the 50 patients treated in the study were immediately
cured, according to results presented at the annual
meeting of the Radiological Society of North America
on November 29.
Bacterial
meningitis dusts for 'metabolic fingerprints'
SYDNEY
A team of Aussie researchers have developed a quick
and accurate method for detecting bacterial meningitis.
The test uses metabonomics the study of the chemical
composition of body tissue and fluids. By comparing
the metabolic fingerprints of spinal fluid from patients
who presented with meningitis-like symptom, researchers
were able to easily distinguish between viral and bacterial
strains. At the moment, most hospitals don't have the
technology required to do the test. But the authors
are hopeful that this test will become more widely available
as costs go down. The study appears in the November
issue of the Journal of Clinical Infection and Disease.
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