JULY 30, 2007
VOLUME 4 NO. 13
 

Nanobubbles pop cancer
SALT LAKE CITY — Tiny bubbles can deliver the chemo drug doxorubicin to tumours without harming surrounding cells, says a July 10 study from the Journal of the National Cancer Institute. "Imagine soap bubbles," one researcher described the technique. "Now imagine a drug in the soap bubbles." The drug-filled polymer nanobubbles are injected into the bloodstream and adhere to tumour cells, where they can be popped by ultrasound. The treatment was effective in mice with human breast cancer tumours.

Killer wrestler's MD charged
ATLANTA — The doctor who supplied steroids to Canadian wrestler Chris Benoit, who killed his wife and son before hanging himself in late June, has been charged with improper prescribing in two other patients' cases. Investigators are considering whether steroid abuse might be to blame in the Benoit case, but Georgia's chief medical examiner says it's impossible to tell. Dr Phil Astin reportedly prescribed 10-months' worth of testosterone to the Montreal-born wrestler every three to four weeks.

TB goes on macro binge
VANCOUVER — How can TB bacilli survive and live inside macrophages, the immune system's hit-men? Thanks to UBC scientist Lindsay Eltis and his team, now we know. Turns out TB gets 'eaten' by the macrophage and proceeds to mooch off the immune cell's cholesterol-rich membrane, according to the February 6 PNAS study. The team also identified the set of genes that allow TB to digest the cholesterol. Next step: targeting those genes in future TB treatments in order to starve the dangerous bacteria to death.

Pet turtle linked to tot's death
ATLANTA — A three-week-old Florida girl died in March from a Salmonella pomona infection soon after her family had been given a small turtle. The Salmonella strain isolated from the turtle was identical to the one that killed the baby. Pet turtles have recently caused Salmonella infections in 11 states, warns the CDC's July 6 Morbidity and Mortality Weekly Report. Eleven percent of all under-21 salmonellosis cases are linked to contact with reptiles and amphibians.

Fortified bread cuts defects
QUEBEC CITY — It's official: food fortification with folic acid dramatically cuts neural-tube defects. Looking at Canadian data from 1993 to 2002, researchers in the July 12 issue of NEJM found a nearly 50% reduction in defects after folic acid was added to cereal products in Canada in 1998. The effect was most pronounced in the eastern half of the country, which had had the highest defect rates. For instance, Newfoundland and Labrador saw defect rates drop from 4.56 per 1,000 to just 0.76.

Pregnant? Sign here
NEW DELHI — India's Women and Child Development Minister wants all pregnant women to register with the government and ask permission for abortions. Renuka Chowdhury told the Hindustan Times that the proposed measure would reduce unsafe abortions of girls — a major problem in India, where boys often get preferential treatment. Prenatal sex-determination tests and abortions on basis of gender — both illegal — pushed down the number of girls per 1,000 boys from 945 in 1991 to 927 in 2001. Women's rights activists call the plan undemocratic and a violation of privacy.

 
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