MARCH 2008
VOLUME 5 NO. 3

ADVANCES in MEDICINE

Dal asthma test bests spirometry

Sensitive device spots "twitchy" airways, easier on kids



Dr Paul Hernandez speaks about the new forced oscillation spirometer (right) in a Dalhousie U video
Photo credit: Dalhousie University/videographer Findlay Muir

A new device cobbled together out of a stereo speaker, some transducers and a breathing tube by scientists at Dalhousie University in Halifax could revolutionize the way we diagnose asthma.

Called a forced oscillation spirometer, the machine measures how resistant or "twitchy" an asthma patient's airways are, explains Dr Paul Hernandez, a Dalhousie respirologist involved in clinical trials of the device, which was developed by Dalhousie biomedical engineer Geoffrey Maksym, PhD. The team has just received a $2 million grant from the Atlantic Innovation Fund to commercialize the device.

"This tool offers new insight into the pathophysiology of asthma and can increase our understanding of asthmatic airways in real time and our detection of asthma," says Dr Hernandez.

Last August the team published a study in the European Respiratory Journal in which they tested the oscillation spirometer on a group of kids with well controlled disease attending an asthma camp and compared the results to non-asthmatic children. They found that the device was a more sensitive way to diagnose who was asthmatic and who wasn't, because the "twitchiness" was detected even though the kids' asthma was well controlled with meds. Dr Hernandez is currently conducting followup studies on the device in adults.

HOW IT WORKS
The patient breathes normally into a tube for about 30 seconds while small puffs of air are being pushed into their lungs. Transducers measure how difficult it is to get the air in and out of their lungs, and from that the clinician knows how resistant or twitchy the airway is. Detecting this twitchiness is hugely important since regular spirometry tests measure only how narrow a patient's airways are, and so might not pick up iffier cases. The other major benefit of the test is that because the patient doesn't have to forcefully exhale, as they do with regular spirometry, it's much easier on kids.

The researchers plan to use their grant windfall to pretty the machine up a bit, make it smaller and start selling it to hospitals and clinics. Halifax's IWK Health Centre and the Mayo Clinic in Rochester, MN are set to use it this year. The finished product will be a two-in-one forced oscillation and standard spirometer, says Dr Hernandez. "I don't think it will be more expensive than the standard version," he says. "The basic equipment isn't very fancy."

One thing Dr Hernandez isn't too hopeful about is getting the machine into the hands of family doctors. "We've had little success trying to get family physicians to use spirometry," he admits. "There are a lot of reasons for it — they don't feel comfortable doing and interpreting the test, there's a small capital cost to getting the machine and most provinces don't reimburse them for doing it."

 

 

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