OCTOBER 30, 2007
VOLUME 4 NO. 18

ADVANCES in MEDICINE

Nerve pulse implant controls bowel movements

Sacral neuromodulation for fecal incontinence aces five-year efficacy trial


A device that helps fecal incontinence sufferers control their bowel movements with an electrical pulse works well in the longterm. That's the conclusion of a Dutch study in October's Journal of Colorectal Disease. The sacral neuromodulation (SNM) implant offered 100 patients near-total control even five years after surgery.

The findings were presented at a session on surgical approaches to fecal incontinence at August's International Surgical Week conference in Montreal. "It shows a clearly improved quality of life," noted Dr Klaus Matzel, commenting on his Dutch colleagues' study. Dr Matzel authored the first paper on sacral nerve stimulation for fecal incontinence in 1995. Sacral nerve stimulation was first used to treat other pelvic disorders, including urinary incontinence.

TAKE BACK CONTROL
Researchers from the University Hospital Maastricht looked at the first 100 permanent implants of the device in patients between 26 and 75 years of age, and found a staggering 79% success rate.

The innovative procedure is the only surgical solution that pre-tests patients for potential success before tackling any major operations. Surgery is only considered for severe cases who haven't responded to drug or behavioural therapy. It is recommended for patients who lost bowel control either due to surgery or disease, but still have an intact anal sphincter.

To select patients who would likely benefit, docs place small needles in the muscles of the lower bowel and stimulate the sacral nerve via an external pulse generator. If these muscles respond properly to stimulation, then the patient gets the green light for a permanent implant.

The surgery is minimally invasive and takes as little as 45 minutes to do, according to Dr Matzel. Once the device is placed in the abdomen, continence is within the patient's reach. A constant stream of electrical pulses keeps the sphincter under tight control. Patients can control their bowel movements by interrupting those pulses. The exact mechanism by which bowel control ensues is still unclear.

Researchers selected 100 patients who experienced at least one episode of fecal incontinence per week and showed a 50% decrease in incontinence episodes after the preliminary test. Eighty-nine of those patients were women, who tend to be the most frequent sufferers of fecal incontinence. Patients were followed over a period of five years, and reported nearly 85% fewer incontinence episodes after the operation.

LIMITED ALTERNATIVES
The SNM implant is still in its infancy in Canada, performed in only a handful of centres. Other surgeries have produced a modest degree of success, such as implant of anal sphincters or nerve transplants, but they are technically complex and they tend to deteriorate over time.

For those who don't respond to other treatments, colostomy is the last resort. Fecal incontinence affects nearly 2% of adult Canadians, most of them elderly. Its causes range from muscle damage — common during childbirth — to disease and nerve damage. First line treatments generally involve dietary changes, medication or bowel training.

 

 

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