AUGUST 30, 2007
VOLUME 4 NO. 14

PATIENTS & PRACTICE

MDs too hasty with ear infection Rx

Acute otitis media guidelines and practice don't match


CPS acute otitis media guidelines

Wait & see A 72-hour observation may be recommended if your patient is over two years old, and follow-up can be arranged.

Choose your weapon AOM is usually bacterial, and amoxicillin's the drug of choice. It's cheap, and just as effective as extended spectrum, penicillinase-resistant oral antibiotics when the cause of AOM is either penicillin-susceptible or -resistant bacteria. It has fewer side effects and may foster less bacterial resistance.

Careful timing 10 days of antibiotics is a safe bet, although the literature isn't clear if this is overkill. An exception: azithromycin is recommended for 5 days.

To jab or not? Parenteral therapy can be considered if barriers to 10-day oral therapy exist, but generally shouldn't be used in simple uncomplicated AOM. There's little evidence they're better than oral treatments, possibly even hastening drug resistance.

Penicillin allergies? Cephalosporins are usually safe, although there's always a possibility of a cross reaction when using beta-lactam alternatives.

Second pass If treatment doesn't clear up pain, fever and irritability in 72 hours, determine if compliance was an issue. Tympanocentesis should be considered -- it can relieve pressure, and guide subsequent antibiotic choice. Amoxicillin clavulanate is an alternative if tympanocentesis isn't practical.

Don't go overboard Middle ear effusion can persist for months. Continued or altered treatment's not suggested if other symptoms are resolved.

Adapted from Canadian Paediatric Society

When doctors manage pediatric acute otitis media (AOM), they don't necessarily practise what they preach, according to a study in the August issue of Pediatrics. The survey of pediatricians exposes a big gap between the recommended guidelines and actual practices.

AOM has an extremely high rate of spontaneous recovery. The American Academy of Pediatrics and the Academy of Physicians guidelines suggest that pediatricians allow a 48-72 hour observation period before they prescribe antibiotics in cases where a diagnosis is uncertain and symptoms aren't severe. Most docs said the suggestion was reasonable, but just not for them -- the approach was used only in a median of 15% of AOM cases.

THE PARENT TRAP
So why don't doctors wait before writing the kid a script? In the Pediatrics study, doctors overwhelmingly blame the parents: mum and dad demand antibiotics for their suffering child, and so doctors oblige. Docs also said follow-up visits are often inconvenient to patients, so they prescribe an antibiotic right off the bat.

Immediate antibiotics for AOM is common practice, but sets off alarm bells in infectious diseases circles. "The increased bacterial resistance to many commonly-used antibiotics poses a serious threat to public health," writes Dutch GP, R A M J Damoiseaux in a CMAJ commentary on the subject. "Nor should we ignore the risks to the individual patient of an allergic reaction, gastrointestinal symptoms or the potential disturbance of the nasopharyngeal flora." The flora issue was raised in a Winnipeg study in June's Chest which linked early antibiotic use to rising asthma rates.

On the other hand, some MDs point out that mastoiditis, which can be a significant cause of child mortality, a common complication of AOM, is greatly reduced when antibiotics are liberally prescribed.

There isn't consensus among Canadian guidelines over what is the best approach, and the literature isn't unequivocal. The Canadian Paediatrics Society's guidelines for AOM propose observation on a case-by-case basis. Other guidelines suggest antibiotics as a first-line treatment.

A middle way is to propose a waiting period to parents. Write a provisional prescription, and tell parents to fill it if their child's symptoms don't clear up in a few days.

 

 

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