APRIL 15, 2007
VOLUME 4 NO. 7

ADVANCES in MEDICINE

Medical twins dream up new surgical device

Prize-winning invention facilitates cutting-edge endoscopic technique



Dr. Margherita Cadeddu (left), assistant professor in the Department of Surgery, works with McMaster medical resident Dr. Adam Power (right) as he experiments with a surgical instrument he invented and has tested as part of his research program.
Photo: Courtesy of McMaster University

A pair of residents has won prize money — and potentially, investor cash — for a new surgical device they developed in Canada.

Dr Adam Power is on leave from McMaster to obtain a master's degree in bioscience enterprise from Cambridge University. His invention is a device that lifts the abdominal wall to facilitate an experimental, "scarless" surgery technique called Natural Orifice Transluminal Endoscopic Surgery (NOTES). He and his twin brother Nicholas, a urology resident at Dalhousie, came up with the idea during their last year of medical school.

NEW FRONTIER
NOTES is a minimally invasive, emerging surgical technique. Just as laparoscopy revolutionized surgery in the 80s and 90s, NOTES aims to take things a step further by doing away with the external incision entirely. Instead, abdominal procedures like appendix or gall bladder removals are performed through an internal incision in the stomach or colon via an endoscope passed through a natural orifice like the mouth or anus. This way, there's no external scarring at all, allowing for even quicker healing times and shorter hospital stays.

As with laparoscopy, however, NOTES requires the abdominal cavity to be inflated with carbon dioxide gas. This leaves abdominal walls prone to collapse on the operative site, lengthens and complicates surgery, and increases post-operative pain.

"[My invention] collapses into a compact form and attaches to a standard endoscope. Once the endoscope enters the abdominal cavity, the instrument is deployed into its expandable form. Then, through our proprietary technology, it lifts the abdominal walls, without the use of gas, providing excellent exposure for the procedure," Dr Power says of his as-yet-unnamed prototype, nicknamed the "Power Tool" by his Cambridge classmates.

At this point, NOTES is more theoretical than practical. In the US, it has been used both diagnostically and therapeutically in animal models, and surgeons in India have published reports on its use in both transoral and transgastric appendectomies. "The allure of scarless operations is hard for patients and physicians to ignore and research continues globally," Dr Power says. "There are many barriers to overcome before the first human trials in NOTES will even begin. Our product addresses one of these barriers and will hopefully help facilitate the safe introduction of the procedure into humans."

GUTS AND GLORY
Dr Power's start-up company, Rem Rom Medical Devices — through which he owns the patents to the instrument — was named one of two runner-ups in an elite business idea challenge between Cambridge and Oxford University students. The competition was presided over by a panel of eminent businesspeople that included multi-millionaire Peter Jones, best known as a panelist on the hit reality TV shows Dragon's Den in the UK and American Inventor in the US. The event was reported by CNN and highlights will be aired on an upcoming British reality TV show, Tycoon.

To date, Dr Power's invention has won him £3,500 (about $8,000CAD) and is vying for another �15,000 (just over $34,000CAD) in the next round of competition. Rem Rom was also recently named as a finalist to "Where Angels May Dare," an event where Dr Power and his teammates will have a chance to pitch the invention to venture capitalists.

The success has been a bit overwhelming, but well deserved for the 29-year-old New Brunswick native. "It feels a bit odd to be gaining recognition for a business idea as someone in the medical field. I know how 'industry' is sometimes viewed by physicians. But I think there's room for more awareness about the industries that help us to treat our patients," he says.

Ultimately, he hopes to partner with a larger medical device company, taking advantage of established manufacturing and distribution capabilities to put his invention in the hands of surgeons just as NOTES enters the clinical trial phase. "When I started medicine, I became drawn to the practical side of things, which is why I decided to go into general surgery. Surgical device innovation was a natural progression," Dr Power says. "But after doing my initial prototype research, I soon realized that coming up with an idea is only a small part of the process."

Dr Power plans to return to McMaster in August to complete the three remaining years of his residency. He will continue to refine his invention, however, while his partners in the UK concentrate on getting the necessary funding — which he estimates at about �50,000 (just under $115,000CAD).

For more information on NOTES, visit the Natural Orifice Surgery Consortium for Assessment and Research's website at www.noscar.org.

 

 

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