APRIL 15, 2006
VOLUME 3 NO. 7

ADVANCES in MEDICINE

Pocket-sized brain imaging tracks trauma

PDA-like device a cheap, tiny alternative to CT



InfraScanner

Researchers at Drexel University in Pennsylvania have created a unique hand-held PDA device to detect brain hematoma following head injury.

When a patient is rushed into the emergency room with severe head trauma, physicians have an hour to figure out just how badly they're hurt — and they need a CT scan to do it. But the prohibitive cost of CT means that a good chunk of brain trauma cases don't get scanned. When you consider that in Canada, 11,000 people die of traumatic brain injuries every year, this is serious business.

The university is hopeful that their InfraScanner will offer physicians a cheaper, quicker alternative for giving the injured brain a quick once-over for those times when CT scans just aren't an option. Pending FDA approval and the completion of a multicentre clinical trial, the device could be available for sale in the US by the end of the year. There's still no word on when it will be available in Canada.

"The new device addresses the critical problem of detecting brain hematoma as early as possible," claims Dr Kambiz Pourrezaei, Drexel University professor of biomedical engineering. "It can also solve the problem of how to find head trauma in children, who are brought to the ER after a crib fall or other injury, without having to wait to determine if a CT scan is needed."

HOW IT WORKS
The InfraScanner should be fairly easy to use. A hairbrush probe is placed on the trauma victim's head and then the PDA communicates wirelessly — using the same Bluetooth wireless technology found in many cell phones and wireless mice — with the probe to produce an image (See illustration, above).

The device detects hematoma using a sophisticated technique of near-infrared brain imaging (fNIR), which can differentiate areas of the brain that are bleeding. This is possible because of the unique way in which hemoglobin interacts with light.

So far, the university's investigators report that trials have gone swimmingly. A pilot study put the device to use on 305 patients so far and all cases of epidural and subdural hematoma were caught. Additionally, 98% of intracerebral hematomas appeared on the InfraScanner's screen. And what's equally important in these time-sensitive trauma cases, researchers found that the InfraScanner tended to catch brain problems more swiftly than conventional monitoring.

WHO NEEDS IT
If the InfraScanner is approved, one of its key benefits will be cost. While no price has been announced, the university website notes the small gadget will surely be significantly cheaper than MRI and CT devices, making it ideal for emergency departments in rural hospitals. "The InfraScanner promises to be a fast, accurate and affordable traumatic brain injury screening solution," Dr Banu Onaral, director of Drexel's School of Biomedical Engineering, Science and Health Systems, and also head of the InfraScanner research effort, told UPI.

"The user-friendly device that maps out the location of the hematoma with graphics on a PDA screen can assist paramedics and emergency room personnel in attending to those injured in traffic and sports accidents, falls and on the battlefield." The InfraScanner's potential to gauge the gravity of injuries on site, far, far away from a CT scanner, led the United States Army and Navy to invest heavily in the research. The National Institutes of Health also contributed to the device's funding.

BORN OUT OF CHANCE
The device is based on an fNIR patent by Dr Britton Chance, Professor Emeritus at University of Pennsylvania, a fascinating man and one of the most prolific scientists of the past century. Now 92-years-old, Dr Chance filed his first patent at the age of 17. Aside from his nearly 70 years of conducting distinguished, eclectic research in medicine, physics, biology and engineering, he also won an Olympic gold medal in 1952 for sailing.

 

 

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