FEBRUARY 15, 2005
VOLUME 2 NO. 3
 

Extreme charity

Live anonymous organ donation: altruism or lunacy?

BC doctors performed the first Canadian anonymous kidney transplants,
and gear up to do more of the same


"I'm not the big hero people make me out to be. I went through a minimal amount of discomfort. It was not a huge sacrifice," said the anonymous donor. "If I had the chance to do it again, I would."

Charity takes many forms — donating to the local food bank or pledging money to the Red Cross, for example. But in British Columbia, some individuals have proven they're capable of taking altruism to a level far beyond that of dropping a few loonies in the tsunami relief jar. Although completely healthy, they've donated kidneys to perfect strangers whom they'll never meet.

In November, the BC Transplant Society (BCTS) announced that it had performed the first two living anonymous donor (LAD) kidney transplants in Canada, as part of a pilot study to confirm the safety and viability of such procedures.

The pilot is the culmination of four years of comprehensive research into the practical and ethical implications of this controversial procedure, which until now has been performed, to the BCTS's knowledge, solely in the US.

DONORS WANTED: DEAD OR ALIVE CLICK HERE (PDF FORMAT)

THEY'D HAVE TO BE NUTS...
Dr David Landsberg, medical director of transplants at St Paul's Hospital in Vancouver and medical director for the BCTS from 1994 until 2003, has been with the project since its inception. He explains that, initially, he was sceptical.

"I can honestly say that I was one of the people who said, 'Of course we can't do this,'" he admits. "I felt that when we look at donors, they have to be mentally stable, and anyone who would do this, by definition, would not be mentally stable."

But when the television program 60 Minutes aired a story in 1999 about an American woman who had anonymously donated one of her kidneys, the BCTS decided to look into the matter more closely. What they discovered about those willing to be anonymous donors, says Dr Landsberg, was surprising.

"We found that a significant number of these people were actually very psychologically intact, and very altruistic," he says. "In fact, they were pretty reasonable people, from a psychological point of view."

DONOR EFFECTS MINIMAL
The results of the donor screening were summed up by Dr Landsberg and his colleagues in a paper entitled "The Living Anonymous Kidney Donor: Lunatic or Saint?", published in the February 2003 issue of the American Journal of Transplantation.

Out of 43 initial potential candidates who had contacted the BCTS of their own volition, 15 were still willing to donate a kidney following an intense assessment of psychological health. Of these, seven were deemed medically unsuitable. For the remaining eight potential donors ok'd for the procedure, Dr Landsberg says the medical risks will be few, and that "the long-term consequences of only having one kidney are, for a healthy person, minimal."

The kidney recipients themselves are far from nonchalant about the life-changing nature of the anonymous donors' gestures. "I have been on dialysis and waiting for a transplant for seven years," said one. "Being off dialysis is huge. I'm feeling better, and this will allow me to return to work."

MORE LADs, PLEASE
Dr Landsberg and his colleagues are planning to facilitate a further eight LAD transplants as part of their pilot study. They will be conducting a follow-up study of the living anonymous donors taking part, in order to determine whether they suffer any psychological ramifications. If all goes well, Dr Landsberg and his team may well have opened up one solution to tackling the drastic organ shortage across the country.

Living donor transplants have been steadily rising in Canada, while cadaveric donations have plateaued (see the graph below). Add longer lifespans to the mix and the BCTS's timing for pushing the transplant envelope couldn't be better.

As of December 31, there were 3,914 Canadians waiting for organ transplants — 73% of them were waiting for kidneys, according to the Canadian Institute for Health Information (CIHI). In 2003, 82 people died while waiting for a kidney.

 

 

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