JANUARY 15, 2005
VOLUME 2 NO. 1
 

Spinach study sheds light on carotenoids' role
in cataract prevention


While solid proof linking spinach to bulging forearms is still missing, Popeye's obsession with the leafy veg may not be completely unfounded. A growing body of evidence indicates that spinach may have other health benefits. A study published in the December issue of the Journal of Nutrition confirms that carotenoids from leafy dark green vegetables like spinach, collard greens and kale can help prevent cataracts.

Human eyes contain two carotenoid molecules, lutein and zeaxanthin, which function as antioxidants. Despite the fact that many over-the-counter vitamin pills and leafy green veggies include these molecules, until now there was no biochemical evidence to support the assumption that they help maintain ocular health.

"Our results are the first to provide physical evidence suggesting that lutein and zeaxanthin decrease damage caused by ultraviolet radiation," said author Dr Joshua Bomser of Ohio State University.

This is big news because ultraviolet (UV) rays wreak havoc in the epithelial layer of the lens by creating free radicals that damage cellular components. This eventually kills the cells and cataracts form as these dead cells clutter up the lens, rendering it opaque.

CELLULAR TAN
The study looked at what happened to cultured human lens epithelial cells in the presence of UV light. The cells were incubated with the concentrations of lutein and zeaxanthin normally present within the eye and then exposed to UV light strong enough to induce a light tan. Cells containing lutein and zeaxanthin were less damaged by radiation exposure and didn't start up their stress response systems as frequently as the control cells. The test cells also contained fewer peroxidated lipid molecules, which are the result of a chemical reaction that occurs when free radicals are loose in the cell.

The researchers are still curious as to how the carotenoids ingested in the diet make their way into the lens because the eye has no vascular system to transport nutrients. Future work will focus on unravelling that mystery.

 

 

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