JUNE 30, 2004
VOLUME 1 NO. 13
 

My gut feeling's that it sucks

Gastric suction in infants raises the risk of functional intestinal symptoms in later life


Having your stomach pumped is really unpleasant, but for some it may be more than just a passing annoyance. How does a lifetime of diarrhea, gas, constipation and cramps sound? A study published in the April issue of the Journal of Pediatrics shows that this may be the trade-off for gastric suction in newborns. While the procedure can stop bilious vomiting in infants born with a blockage of the intestinal tract, this life-saving intervention may pave the way for irritable bowel syndrome (IBS) further down the road.

The link, according to Dr Kanwaljeet 'Sunny' Anand, a pediatrician and researcher at the Arkansas Children's Hospital in Little Rock, lies in a shift in brain development that's somehow triggered by noxious stimulation like gastric suction. Dr Anand's research sheds light on "the longterm impact of experiences that occur during critical windows of early development."

To support this novel concept, Dr Anand and his colleagues looked at the birth records of 494 American mothers who'd delivered two or more children of normal birth weight, at least one of whom had perinatal complications or difficulty breathing. Among the 1,110 infants, 108 were later hospitalized for 'functional intestinal symptoms.' Of these, 96 were compared to 116 unaffected siblings to investigate the link between gastric suction and intestinal difficulties.

They found that almost 23% of the 108 children had had their stomachs pumped a few days after birth while only 11.2% of their intestinally normal siblings had also undergone the procedure. Statistical analyses confirmed that the control and case populations were similar in terms of pre-birth complications and the incidence of breathing difficulties after birth, and that family medical history did not play a role.

Compared with their siblings, infants who underwent gastric suctioning had an almost three-fold increased risk of developing an intestinal disorder, even years later. The researchers believed that adverse conditions in early life may trigger altered brain development, causing disorders like visceral hypersensitivity -- a heightened sensory network. This is thought to be one of the underlying roots of functional intestinal disorders, such as IBS, which is estimated to afflict one in five Canadians.

One of them is Jeffrey Roberts. "As a very young child I had my stomach pumped after ingesting a large quantity of medication. I have always believed that this event contributed to my own development of IBS," said Mr Roberts, president and founder of the IBS Association/IBS Self Help Group of Canada.

What will be the outcome of this latest research? According to an editorial that accompanies the Journal of Pediatrics paper, while it's still too early to recommend modifications in the care of newborns, avoiding unnecessary and uncomfortable procedures in this critical time is always wise.

 

 

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