OCTOBER 30, 2004
VOLUME 1 NO. 20
 

Transplant Timeline



To view the Transplant Timeline click here. (pdf format)

500 BC According to Chinese legend, doctor Pien Ch’iao performs a dual-heart transplant on warriors Gong Hu and Qi Ying 1742 Swiss Abraham Trembley successfully transplants tissue between hydras 1920 In France, Dr Serge Voronoff pioneers a technique of grafting monkey testicles onto humans. He performs an estimated 500 such procedures on the rich and foolish before he’s pressured to stop by colleagues in the early 1930s 1944 Sir Peter Medawar first discovers the immune system is to blame for the failure of all previous organ transplant experiments 1955 Torontonian Dr Gordon Murray performs the first heart valve transplant; the heart valve keeps working for over 8 years 1963 Dr James Hardy attempts the first human lung transplant; the recipient dies the same night 1964 Dr Starzl next tries to transplant six baboon kidneys into humans. Most of the patients die soon after but one lives 98 days 1967 South African surgeon Dr Christian Barnard performs the first successful human heart transplant. The patient only lives another 18 days, but it is pneumonia that kills him — the heart was still working 1969 In the first successful temporary artificial heart implant, Dr Denton Cooley of Houston uses the ‘Liotta Total Artificial Heart’ to keep a patient alive until a donor heart becomes available three days later 1979 Dr David Sutherland performs the first living-donor partial pancreas transplant. (The first ever pancreas transplant was performed at the same University of Minnesota lab in 1966) 1982 Dr William DeVries implants the first permanent artificial heart (called the ‘Jarvik-7’) into Barney Clark of Salt Lake City. Mr Clark lives 112 days after the procedure 1984 A baboon heart is transplanted into 15-month-old ‘baby Faye;’ it works for 20 days 2003 After an intense 14-hour procedure, Dr Christian Kermer and Dr Franz Watzinger of Vienna’s General Hospital successfully transplant a tongue into a patient. While taste isn’t restored and the recipient can’t move the tongue on his own, he is soon able to swallow liquid

200 AD Hua Tuo, another legendary Chinese physician, performs therapeutic organ transplants 1901-1903 Austrian Dr Karl Landsteiner discovers the ABO blood classifications 1936 Russian Dr Voronoy performs the first human kidney transplant; the recipient survives four days 1954 Dr Joseph E Murray performs the first successful kidney transplant in Boston, transplanting Ronald Herrick’s kidney into his twin brother Richard. Richard marries his nurse and lives another eight years 1958 Dr Jean Dausset discovers the antigen, HLA-A2, which will make it easier to work with organs of different blood types 1963 Colorado-based Dr Thomas E Starzl attempts the first human liver transplant but the patient quickly rejects the new organ 1964 Dr James Hardy tries using a chimpanzee heart in a case where the patient’s heart had failed and no human donor was available. It only works for 90 minutes 1967 Dr Starzl jumps previous hurdles and performs the first successful liver transplant 1977 The immunosuppressive drug cyclosporine is introduced by Dr Jean Borel. The discovery comes out of his studies of the fungus Beauveria nivea, native to Norwegian mud 1981 Stanford surgeon Dr Bruce Reitz successfully performs a heart-lung transplant using cyclosporine (then still in testing) as an anti-rejection drug 1983 Toronto General Hospital surgeon, Dr Joel Cooper, successfully transplants a lung in a 58-year-old man, who lives another six years 1986 Canada’s Dr Joel Cooper strikes again, performing the breathtaking (or breath-giving) first-ever double-lung transplant. The patient dies of an unrelated illness 15 years later

 

 

 

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