SEPTEMBER 23, 2004
VOLUME 1 NO. 17
 

Prolonged constipation predicts poor outcomes in kids

Researchers strain to find the link between colonic transit time and Tx success


Nine-year-old Lucia Caceres' face contorts with effort as her mother exhorts her to push. No, Lucia isn't contending for the title of world's youngest mother, she's merely trying, unsuccessfully, to empty her bowels. Constipation is hard enough to endure for an adult. But, as Lucia's mom can attest, failing to poop can be even more uncomfortable and traumatic for a child. Now, compounding the worry, comes news that a prolonged bout of constipation can set a child up for more bathroom difficulties in the future.

Dutch researchers, headed by Dr F de Lorijn of Emma Children's Hospital in Amsterdam, have published a paper in the August issue of Archives of Disease in Childhood documenting that a colonic transit time � the time it takes waste to move through the large intestine � that exceeds 100 hours can predict the success, or more accurately the failure, of bowel-unplugging treatments.

If the colonic transit time exceeds 100 hours, a child's chances of having constipation problems a year down the road are high. The study involved 169 consecutive patients (110 boys and 59 girls) with an average age of 8.5 years who were seen by the Dutch researchers between 1995 and 2000. All the patients had less than three bowel movements a week, most of which were involuntary. The children also had a very large bowel movement every one to four weeks and had a mass of feces that could be felt by palpation of the rectum or abdomen.

The colonic transit time was determined by x-ray examination when each child first entered the study. The children were treated in a variety of standard ways, such as eating foods high in fiber, taking laxatives and using biofeedback as a behavioural modification strategy. In exceptional cases, an enema was given to dislodge the feces quickly. While in treatment and for some time afterward, each child was encouraged to keep a diary to record their symptoms.

The frequency of urgent and involuntary bowel movements was higher in the boys who also had fewer bowel movements than girls. Colonic transit times were significantly longer in kids who averaged one or less bowel movements a week as compared to those who had more frequent bathroom trips. The ensuing year brought continued constipational woes for the 22% of children who had a colonic transit time measured at over 100 hours.

Dr de Lorijn and colleagues were led to the somewhat dismal conclusion that "the diagnostic and prognostic role of [colonic transit time] measurements is limited." More optimistically though, the finding that a colonic transit time exceeding 100 hours "is associated with a poor outcome at one year" might prove to be a helpful guidepost for targeting treatment.

 

 

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